Identity

Nitrofurans are an active chemical compound class (synthetic broad-spectrum antibacterial compounds) whose use is strictly prohibited within the poultry sector.

Overview

Nitrofurans (including formulations like Furaltadone) are categorized as banned substances in the Indian poultry industry. The government (CDSCO Veterinary Division) enforced a complete ban on their import, manufacture, sale, and use in food-producing animal rearing on 12.03.2025. They are classified as carcinogens and mutagens, and ensuring absolute compliance with this restriction is a critical regulatory priority.

Structured Facts

Indications

Banned Substance.

Mechanism of Action

Nitrofurans undergo enzymatic reduction inside the bacterial cell, generating highly reactive, short-lived electrophilic intermediates. These intermediates damage bacterial DNA, proteins, and ribosomal structures, halting macromolecular synthesis.

Dosage

Not specified in sources (Prohibited)

Withdrawal Period

Not applicable (complete ban).

Contraindications

Complete ban for use in poultry, food-producing animals, and animal rearing.

Adverse Effects

Nitrofurans are classified as carcinogens and mutagens. The parent compounds degrade rapidly in vivo into highly stable, protein-bound tissue metabolites (such as AOZ and AMOZ) that persist in structural tissues.

Quantitative Data

• Withdrawal: Not applicable (Banned)

Relationships