Identity

Chloramphenicol is a broad-spectrum amphenicol antibiotic whose use is strictly prohibited within the poultry sector.

Overview

Chloramphenicol is categorized as a banned substance in the Indian poultry industry. The Central Drugs Standard Control Organization (CDSCO) Veterinary Division enforced an absolute ban on its import, manufacture, sale, distribution, and use in all food-producing animal rearing systems on 12.03.2025 to prevent veterinary drug residues and mitigate antimicrobial resistance. Ensuring absolute compliance with this restriction is a critical regulatory priority.

Structured Facts

Indications

Banned Substance.

Mechanism of Action

Binds reversibly to the peptidyl transferase center of the 50S ribosomal subunit, preventing peptide bond formation during protein synthesis.

Dosage

Not specified in sources (Prohibited)

Withdrawal Period

Not applicable (complete ban).

Contraindications

Banned for use in poultry and animal rearing.

Adverse Effects

In food-producing animals, chloramphenicol is associated with a severe dose-independent adverse reaction in humans: irreversible aplastic anemia. Promotes global antimicrobial resistance.

Quantitative Data

• Withdrawal: Not applicable (Banned)

Relationships

• Resistance: Promotes global antimicrobial resistance.