[{"data":1,"prerenderedAt":1312},["ShallowReactive",2],{"Footer_8bXNFXYX6wgkC5g8iX784dLp8jDy4Cs1s4DQNBlZm7A":3,"content-\u002Fen\u002Fdiseases\u002Fchicken-infectious-anemia":10,"related-\u002Fen\u002Fdiseases\u002Fchicken-infectious-anemia":240},["Island",4],{"key":5,"result":6},"Footer_8bXNFXYX6wgkC5g8iX784dLp8jDy4Cs1s4DQNBlZm7A",{"head":7},{"link":8,"style":9},[],[],{"id":11,"title":12,"author":13,"body":14,"category":169,"day":170,"description":12,"editorialReview":171,"extension":172,"featuredCategories":170,"futureReady":170,"handoff":170,"hero":170,"homepageSections":170,"language":173,"lastUpdated":174,"meta":175,"navigation":177,"path":178,"phase":170,"practical":179,"seo":216,"sequence":170,"stats":170,"stem":237,"tags":170,"translationVersion":238,"version":238,"whyKodiBook":170,"__hash__":239},"content\u002Fen\u002Fdiseases\u002Fchicken-infectious-anemia.md","Chicken Infectious Anemia in Poultry","KodiBook Digital Research Team",{"type":15,"value":16,"toc":158},"minimark",[17,22,26,30,33,37,42,45,49,74,78,89,93,104,108,113,117,128,132,143,147],[18,19,21],"h1",{"id":20},"identity","Identity",[23,24,25],"p",{},"An acute, immunosuppressive viral disease of young chickens caused by the Chicken Anemia Virus (CAV). It targets hemocytoblasts in the bone marrow and T-lymphocytes in the thymus, causing aplastic anemia, generalized lymphoid atrophy, and severe immunosuppression.",[18,27,29],{"id":28},"overview","Overview",[23,31,32],{},"Chicken Infectious Anemia (CIA) is a high-priority immunosuppressive virus characterized by its small, single-stranded DNA genome. The virus selectively induces apoptosis (via the VP3 apoptin protein) in bone marrow hemocytoblasts and cortical thymic T-lymphocytes. This results in severe anemia and a critically compromised cell-mediated immune system. Young chicks (\u003C3 weeks) show clinical disease, while older birds suffer subclinical immunosuppression. Prevention relies entirely on ensuring breeder flocks are actively vaccinated (live CAV vaccines) prior to lay to ensure the vertical transfer of protective maternal antibodies to progeny, preventing devastating secondary infections.",[18,34,36],{"id":35},"structured-facts","Structured Facts",[38,39,41],"h2",{"id":40},"classification","Classification",[23,43,44],{},"Viral > Infectious Pathogen",[38,46,48],{"id":47},"epidemiology","Epidemiology",[50,51,52,56,59,62,65,68,71],"ul",{},[53,54,55],"li",{},"Severity: High (due to immunosuppression\u002Fvaccine failure)",[53,57,58],{},"Affected Species: Poultry",[53,60,61],{},"Affected Age: Young chicks \u003C 3 weeks of age (clinical); older birds (subclinical)",[53,63,64],{},"Transmission: Vertical (transovarian shedding for 3-6 weeks if breeder infected during lay); Horizontal (fecal-oral)",[53,66,67],{},"Mortality: 10% to 20% (uncomplicated), >60% with secondary bacterial complications",[53,69,70],{},"Morbidity: High in chicks from non-immune breeders",[53,72,73],{},"Economic Importance: High (immunosuppression leads to secondary infections and vaccine failure)",[38,75,77],{"id":76},"clinical-signs","Clinical Signs",[50,79,80,83,86],{},[53,81,82],{},"Early\u002FIntermediate: Severe depression, progressive pallor of the comb, wattles, and skin, weight loss",[53,84,85],{},"Advanced: Subcutaneous hemorrhages, localized necrotic dermatitis on wings (\"blue wing disease\"); targets Hematopoietic (bone marrow) and Immune systems (thymus)",[53,87,88],{},"Postmortem Findings: Severe atrophy of the thymus and bursa of Fabricius; pale yellow, fatty bone marrow in the femur; subcutaneous\u002Fintramuscular hemorrhages in breast and thigh.",[38,90,92],{"id":91},"diagnosis","Diagnosis",[50,94,95,98,101],{},[53,96,97],{},"Field Diagnosis: Pale chicks with severe thymic atrophy and fatty bone marrow",[53,99,100],{},"Laboratory Tests: PCR, ELISA (to monitor breeder flock titers), Histopathology (thymic cortical lymphocyte depletion)",[53,102,103],{},"Differential Diagnosis: Infectious Bursal Disease, Aflatoxicosis, Sulfa drug toxicity",[38,105,107],{"id":106},"treatment","Treatment",[50,109,110],{},[53,111,112],{},"Medicines: None exist",[38,114,116],{"id":115},"prevention","Prevention",[50,118,119,122,125],{},[53,120,121],{},"Vaccination: Live CAV vaccines for commercial breeders (drinking water\u002Finjection) administered between 13 and 15 weeks of age (prior to lay)",[53,123,124],{},"Biosecurity: Mitigated by standard Biosecurity Protocols",[53,126,127],{},"Farm Management: Ensure maternal antibody transfer to progeny",[18,129,131],{"id":130},"quantitative-data","Quantitative Data",[50,133,134,137,140],{},[53,135,136],{},"Morbidity Rate: High",[53,138,139],{},"Mortality Rate: 10-20% (uncomplicated), >60% (complicated)",[53,141,142],{},"Target Age: \u003C 3 weeks",[18,144,146],{"id":145},"relationships","Relationships",[50,148,149,152,155],{},[53,150,151],{},"Vaccines: Live CAV vaccines (Breeders)",[53,153,154],{},"Medicines: None",[53,156,157],{},"Predisposing Relationships: Strongly synergistic with IBDV or Marek's Disease, leading to gangrenous dermatitis and secondary opportunistic infections.",{"title":159,"searchDepth":160,"depth":160,"links":161},"",3,[162,164,165,166,167,168],{"id":40,"depth":163,"text":41},2,{"id":47,"depth":163,"text":48},{"id":76,"depth":163,"text":77},{"id":91,"depth":163,"text":92},{"id":106,"depth":163,"text":107},{"id":115,"depth":163,"text":116},"diseases",null,"KodiBook Editorial Team","md","en","2026-06-27",{"puid":176,"readingTime":163},"puid_poultry_01a051e7-a00d-7df7-a2fc-ed73f046573b",true,"\u002Fen\u002Fdiseases\u002Fchicken-infectious-anemia",{"entityId":159,"entityType":180,"language":173,"slug":181,"atAGlance":182,"whatYouMayNotice":186,"whyItMatters":196,"whatToCheck":197,"practicalProtocol":207,"preventionControl":208,"veterinaryEscalation":215,"hasPracticalData":177},"disease","chicken-infectious-anemia",[183],{"label":184,"value":185},"Severity Level","High",[187,190,193],{"label":188,"value":189},"Early Signs","Severe depression, progressive pallor of the comb, wattles, and skin, weight loss",{"label":191,"value":192},"Advanced Symptoms","Subcutaneous hemorrhages, localized necrotic dermatitis on wings (\"blue wing disease\"); targets Hematopoietic (bone marrow) and Immune systems (thymus)",{"label":194,"value":195},"Postmortem Findings","Severe atrophy of the thymus and bursa of Fabricius; pale yellow, fatty bone marrow in the femur; subcutaneous\u002Fintramuscular hemorrhages in breast and thigh.",[],[198,201,204],{"label":199,"value":200},"Field Verification","Pale chicks with severe thymic atrophy and fatty bone marrow",{"label":202,"value":203},"Laboratory Confirmation","PCR, ELISA (to monitor breeder flock titers), Histopathology (thymic cortical lymphocyte depletion)",{"label":205,"value":206},"Differential Possibilities","Infectious Bursal Disease, Aflatoxicosis, Sulfa drug toxicity",[],[209,212],{"label":210,"value":211},"Vaccination Control","Hatchery standard or field boosting",{"label":213,"value":214},"Biosecurity Action","Mitigated by standard Biosecurity Protocols",[],{"keywords":217,"canonical":220,"hreflangs":221,"schemas":235,"title":12,"description":12},[169,218,219,173],"poultry farming","kodibook guide","https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Fchicken-infectious-anemia\u002F",[222,223,226,229,232],{"lang":173,"href":220},{"lang":224,"href":225},"hi","https:\u002F\u002Fkodibook.com\u002Fhi\u002Fdiseases\u002Fchicken-infectious-anemia\u002F",{"lang":227,"href":228},"te","https:\u002F\u002Fkodibook.com\u002Fte\u002Fdiseases\u002Fchicken-infectious-anemia\u002F",{"lang":230,"href":231},"ta","https:\u002F\u002Fkodibook.com\u002Fta\u002Fdiseases\u002Fchicken-infectious-anemia\u002F",{"lang":233,"href":234},"kn","https:\u002F\u002Fkodibook.com\u002Fkn\u002Fdiseases\u002Fchicken-infectious-anemia\u002F",[236],"{\"@context\":\"https:\u002F\u002Fschema.org\",\"@type\":\"TechArticle\",\"headline\":\"Chicken Infectious Anemia in Poultry\",\"description\":\"Chicken Infectious Anemia in Poultry\",\"identifier\":\"puid_poultry_01a051e7-a00d-7df7-a2fc-ed73f046573b\",\"inLanguage\":\"en\",\"url\":\"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Fchicken-infectious-anemia\u002F\",\"author\":{\"@type\":\"Organization\",\"name\":\"KodiBook\",\"url\":\"https:\u002F\u002Fkodibook.com\"}}","en\u002Fdiseases\u002Fchicken-infectious-anemia",1,"c7UFSKD7kLERtn3pSJ0FAohh8yiT9uCaA6JJe9YlfTc",[241,446,645,838,1071],{"id":242,"title":243,"author":13,"body":244,"category":169,"day":170,"description":243,"editorialReview":171,"extension":172,"featuredCategories":170,"futureReady":170,"handoff":170,"hero":170,"homepageSections":170,"language":173,"lastUpdated":174,"meta":389,"navigation":177,"path":391,"phase":170,"practical":392,"seo":429,"sequence":170,"stats":170,"stem":444,"tags":170,"translationVersion":238,"version":238,"whyKodiBook":170,"__hash__":445},"content\u002Fen\u002Fdiseases\u002Faflatoxicosis.md","Aflatoxicosis in Poultry",{"type":15,"value":245,"toc":381},[246,248,251,253,256,258,260,263,265,294,296,307,309,320,322,336,338,349,351,368,370],[18,247,21],{"id":20},[23,249,250],{},"A critical, systemic toxicological disease caused by ingestion of aflatoxins produced by moldy feed. It severely targets hepatic protein synthesis, leading to liver damage, lipid accumulation, and critical immunosuppression resulting in vaccination failures.",[18,252,29],{"id":28},[23,254,255],{},"Aflatoxicosis is a critical toxicological pathogen driven by highly toxic secondary metabolites (primarily Aflatoxin B1). Molds grow on feed ingredients (maize, groundnut) when moisture >15% and humidity >75%. The toxins are metabolized in the liver into reactive epoxides that covalently bind to DNA\u002FRNA, halting protein synthesis and causing severe hepatic lipid accumulation. This results in profound immunosuppression (failure of NDV\u002FIBD vaccines) and predisposes flocks to secondary diseases like Colibacillosis and Visceral Gout. Prevention relies on testing raw ingredients (rejecting >20 ppb) and utilizing feed-based toxin binders (HSCAS).",[18,257,36],{"id":35},[38,259,41],{"id":40},[23,261,262],{},"Toxicological > Non-Infectious",[38,264,48],{"id":47},[50,266,267,270,273,276,279,282,285,288,291],{},[53,268,269],{},"Prevalence in India: Widespread feed contamination",[53,271,272],{},"Severity: Critical",[53,274,275],{},"Affected Species: Poultry (Broilers and ducklings highly susceptible)",[53,277,278],{},"Affected Age: All ages",[53,280,281],{},"Transmission: Ingestion of contaminated feed",[53,283,284],{},"Seasonality: Associated with warm ambient temperatures (25°C to 35°C) and high humidity",[53,286,287],{},"Mortality: 5% to 30% (acute)",[53,289,290],{},"Morbidity: Approaches 100% in exposed flocks",[53,292,293],{},"Economic Importance: Critical (FCR impact, severe public health risk via milk\u002Fegg residues AFM1)",[38,295,77],{"id":76},[50,297,298,301,304],{},[53,299,300],{},"Early\u002FIntermediate: Drop in feed intake, stunted growth, poor feathering, increased bruising",[53,302,303],{},"Advanced: Severe immunosuppression, targets Hepatic and Coagulation systems",[53,305,306],{},"Postmortem Findings: Enlarged, pale-yellow, greasy, friable liver with subcapsular petechiae. Enlarged gallbladder with thick green bile. Severe atrophy of bursa of Fabricius, thymus, and spleen.",[38,308,92],{"id":91},[50,310,311,314,317],{},[53,312,313],{},"Field Diagnosis: Stunted flocks with pale greasy livers",[53,315,316],{},"Laboratory Tests: HPLC or ELISA of feed samples to quantify aflatoxin levels. Histopathology: hepatocellular vacuolization, biliary hyperplasia.",[53,318,319],{},"Differential Diagnosis: Fatty Liver Hemorrhagic Syndrome, Inclusion Body Hepatitis",[38,321,107],{"id":106},[50,323,324,327,330,333],{},[53,325,326],{},"Immediate Actions: Remove contaminated feed",[53,328,329],{},"Supportive Care: Lipotropic factors (choline, methionine) and Vitamin therapy",[53,331,332],{},"Medicines: High-affinity toxin binders (Hydrated Sodium Calcium Aluminosilicate - HSCAS)",[53,334,335],{},"Withdrawal: Not applicable",[38,337,116],{"id":115},[50,339,340,343,346],{},[53,341,342],{},"Vaccination: None (Aflatoxicosis causes vaccination failure for other diseases)",[53,344,345],{},"Biosecurity: Feed screening (rejecting > 20 ppb)",[53,347,348],{},"Farm Management: Maintain feed moisture \u003C 12%, use multi-functional mycotoxin binders",[18,350,131],{"id":130},[50,352,353,356,359,362,365],{},[53,354,355],{},"Morbidity Rate: 100%",[53,357,358],{},"Mortality Rate: 5% to 30% (Acute)",[53,360,361],{},"Regulatory Threshold: > 20 ppb (rejection)",[53,363,364],{},"Environmental Triggers: Moisture > 15%, Humidity > 75%, Temp 25-35°C",[53,366,367],{},"Safe Moisture Level: \u003C 12%",[18,369,146],{"id":145},[50,371,372,375,378],{},[53,373,374],{},"Vaccines: Impairs efficacy of NDV and IBDV vaccines",[53,376,377],{},"Medicines: HSCAS (Toxin Binders), Choline, Methionine",[53,379,380],{},"Related Diseases: Colibacillosis, Visceral Gout, Systemic Mycotoxicosis",{"title":159,"searchDepth":160,"depth":160,"links":382},[383,384,385,386,387,388],{"id":40,"depth":163,"text":41},{"id":47,"depth":163,"text":48},{"id":76,"depth":163,"text":77},{"id":91,"depth":163,"text":92},{"id":106,"depth":163,"text":107},{"id":115,"depth":163,"text":116},{"puid":390,"readingTime":163},"puid_poultry_01a051e7-a00c-7b14-aaf2-9eeb8edc68d2","\u002Fen\u002Fdiseases\u002Faflatoxicosis",{"entityId":159,"entityType":180,"language":173,"slug":393,"atAGlance":394,"whatYouMayNotice":402,"whyItMatters":409,"whatToCheck":416,"practicalProtocol":423,"preventionControl":424,"veterinaryEscalation":428,"hasPracticalData":177},"aflatoxicosis",[395,396,399],{"label":184,"value":185},{"label":397,"value":398},"Mainly Affected","All ages",{"label":400,"value":401},"Spread Route","Ingestion of contaminated feed",[403,405,407],{"label":188,"value":404},"Drop in feed intake, stunted growth, poor feathering, increased bruising",{"label":191,"value":406},"Severe immunosuppression, targets Hepatic and Coagulation systems",{"label":194,"value":408},"Enlarged, pale-yellow, greasy, friable liver with subcapsular petechiae. Enlarged gallbladder with thick green bile. Severe atrophy of bursa of Fabricius, thymus, and spleen.",[410,413],{"label":411,"value":412},"Reported Mortality","5% to 30% (acute)",{"label":414,"value":415},"Economic Risk","Critical (FCR impact, severe public health risk via milk\u002Fegg residues AFM1)",[417,419,421],{"label":199,"value":418},"Stunted flocks with pale greasy livers",{"label":202,"value":420},"HPLC or ELISA of feed samples to quantify aflatoxin levels. Histopathology: hepatocellular vacuolization, biliary hyperplasia.",{"label":205,"value":422},"Fatty Liver Hemorrhagic Syndrome, Inclusion Body Hepatitis",[],[425,426],{"label":210,"value":211},{"label":213,"value":427},"Feed screening (rejecting > 20 ppb)",[],{"keywords":430,"canonical":431,"hreflangs":432,"schemas":442,"title":243,"description":243},[169,218,219,173],"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Faflatoxicosis\u002F",[433,434,436,438,440],{"lang":173,"href":431},{"lang":224,"href":435},"https:\u002F\u002Fkodibook.com\u002Fhi\u002Fdiseases\u002Faflatoxicosis\u002F",{"lang":227,"href":437},"https:\u002F\u002Fkodibook.com\u002Fte\u002Fdiseases\u002Faflatoxicosis\u002F",{"lang":230,"href":439},"https:\u002F\u002Fkodibook.com\u002Fta\u002Fdiseases\u002Faflatoxicosis\u002F",{"lang":233,"href":441},"https:\u002F\u002Fkodibook.com\u002Fkn\u002Fdiseases\u002Faflatoxicosis\u002F",[443],"{\"@context\":\"https:\u002F\u002Fschema.org\",\"@type\":\"TechArticle\",\"headline\":\"Aflatoxicosis in Poultry\",\"description\":\"Aflatoxicosis in Poultry\",\"identifier\":\"puid_poultry_01a051e7-a00c-7b14-aaf2-9eeb8edc68d2\",\"inLanguage\":\"en\",\"url\":\"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Faflatoxicosis\u002F\",\"author\":{\"@type\":\"Organization\",\"name\":\"KodiBook\",\"url\":\"https:\u002F\u002Fkodibook.com\"}}","en\u002Fdiseases\u002Faflatoxicosis","Oa3u0UQKoKA7jiEQuw8XR-N2fT7LEDmljVm1Hj3X1X4",{"id":447,"title":448,"author":13,"body":449,"category":169,"day":170,"description":448,"editorialReview":171,"extension":172,"featuredCategories":170,"futureReady":170,"handoff":170,"hero":170,"homepageSections":170,"language":173,"lastUpdated":174,"meta":593,"navigation":177,"path":595,"phase":170,"practical":596,"seo":628,"sequence":170,"stats":170,"stem":643,"tags":170,"translationVersion":238,"version":238,"whyKodiBook":170,"__hash__":644},"content\u002Fen\u002Fdiseases\u002Fammonia-toxicity.md","Ammonia Toxicity",{"type":15,"value":450,"toc":585},[451,453,456,458,461,463,465,468,470,498,500,511,513,524,526,535,537,548,550,567,569],[18,452,21],{"id":20},[23,454,455],{},"An environmental, non-infectious condition caused by the accumulation of ammonia gas from fecal decomposition. The gas forms alkaline ammonium hydroxide on mucosal surfaces, causing severe corneal ulceration and paralyzing tracheal cilia.",[18,457,29],{"id":28},[23,459,460],{},"Ammonia Toxicity is a major environmental disorder in intensive poultry housing. High litter moisture, high pH, and poor ventilation accelerate microbial uric acid breakdown into NH3. Exposure directly burns the cornea causing blindness (at >50 ppm) and paralyzes the tracheal mucociliary escalator (deciliation at >25 ppm). This directly predisposes flocks to secondary colisepticemia. Management requires continuous electrochemical sensing to keep levels below 20 ppm, utilizing ventilation, daily litter raking, and litter acidifiers (alum) to convert volatile ammonia into stable ammonium.",[18,462,36],{"id":35},[38,464,41],{"id":40},[23,466,467],{},"Environmental > Non-Infectious",[38,469,48],{"id":47},[50,471,472,475,478,480,483,486,489,492,495],{},[53,473,474],{},"Prevalence in India: Highly prevalent in intensive housing",[53,476,477],{},"Severity: High",[53,479,58],{},[53,481,482],{},"Affected Age: All age groups; growing broilers show high susceptibility",[53,484,485],{},"Transmission: Non-infectious (environmental exposure)",[53,487,488],{},"Seasonality: Associated with wet litter\u002Fpoor ventilation",[53,490,491],{},"Mortality: 10% to 15% (indirectly, due to secondary respiratory infections)",[53,493,494],{},"Morbidity: High in poorly ventilated houses",[53,496,497],{},"Economic Importance: High",[38,499,77],{"id":76},[50,501,502,505,508],{},[53,503,504],{},"Early\u002FIntermediate: Squinting, blinking, watery eyes, conjunctivitis, severe photophobia, blepharo-spasm. Respiratory: tracheal rales, coughing, sneezing.",[53,506,507],{},"Advanced: Corneal ulcers, blindness; targets Respiratory and Integumentary (Ocular) systems.",[53,509,510],{},"Postmortem Findings: Severe conjunctival congestion, corneal edema\u002Fulceration, tracheal mucosal congestion with loss of ciliated epithelial layer.",[38,512,92],{"id":91},[50,514,515,518,521],{},[53,516,517],{},"Field Diagnosis: Ocular irritation, strong ammonia smell",[53,519,520],{},"Laboratory Tests: Colorimetric indicator tubes or electronic gas detectors; Histopathology showing tracheal deciliation",[53,522,523],{},"Differential Diagnosis: Infectious Laryngotracheitis, Newcastle Disease",[38,525,107],{"id":106},[50,527,528,531,533],{},[53,529,530],{},"Immediate Actions: Turn fans on (via Ammonia Reduction Tree protocol), improve ventilation",[53,532,154],{},[53,534,335],{},[38,536,116],{"id":115},[50,538,539,542,545],{},[53,540,541],{},"Vaccination: None",[53,543,544],{},"Biosecurity: Not applicable",[53,546,547],{},"Farm Management: Regulate curtain position; daily tilling of litter; use litter conditioners (aluminum sulfate \u002F alum, sodium bisulfate) to lower pH; maintain litter moisture \u003C 25%.",[18,549,131],{"id":130},[50,551,552,555,558,561,564],{},[53,553,554],{},"Safe Threshold: \u003C 20 ppm",[53,556,557],{},"Deciliation Threshold: > 25 ppm",[53,559,560],{},"Corneal Ulcer Threshold: > 50 ppm",[53,562,563],{},"Indirect Mortality: 10% to 15%",[53,565,566],{},"Litter Moisture Target: \u003C 25%",[18,568,146],{"id":145},[50,570,571,574,576,579,582],{},[53,572,573],{},"Vaccines: None",[53,575,154],{},[53,577,578],{},"Management Protocols: Ammonia Reduction Tree, Alum Litter Treatment, Curtain adjustment",[53,580,581],{},"Equipment: Ammonia Electrochemical Sensor, Gas Detectors",[53,583,584],{},"Predisposing Relationships: Severe trigger for Avian Pathogenic Escherichia coli (Colibacillosis)",{"title":159,"searchDepth":160,"depth":160,"links":586},[587,588,589,590,591,592],{"id":40,"depth":163,"text":41},{"id":47,"depth":163,"text":48},{"id":76,"depth":163,"text":77},{"id":91,"depth":163,"text":92},{"id":106,"depth":163,"text":107},{"id":115,"depth":163,"text":116},{"puid":594,"readingTime":163},"puid_poultry_01a051e7-a00c-7b45-b96b-398f2ced898e","\u002Fen\u002Fdiseases\u002Fammonia-toxicity",{"entityId":159,"entityType":180,"language":173,"slug":597,"atAGlance":598,"whatYouMayNotice":604,"whyItMatters":611,"whatToCheck":615,"practicalProtocol":622,"preventionControl":623,"veterinaryEscalation":627,"hasPracticalData":177},"ammonia-toxicity",[599,600,602],{"label":184,"value":185},{"label":397,"value":601},"All age groups; growing broilers show high susceptibility",{"label":400,"value":603},"Non-infectious (environmental exposure)",[605,607,609],{"label":188,"value":606},"Squinting, blinking, watery eyes, conjunctivitis, severe photophobia, blepharo-spasm. Respiratory: tracheal rales, coughing, sneezing.",{"label":191,"value":608},"Corneal ulcers, blindness; targets Respiratory and Integumentary (Ocular) systems.",{"label":194,"value":610},"Severe conjunctival congestion, corneal edema\u002Fulceration, tracheal mucosal congestion with loss of ciliated epithelial layer.",[612,614],{"label":411,"value":613},"10% to 15% (indirectly, due to secondary respiratory infections)",{"label":414,"value":185},[616,618,620],{"label":199,"value":617},"Ocular irritation, strong ammonia smell",{"label":202,"value":619},"Colorimetric indicator tubes or electronic gas detectors; Histopathology showing tracheal deciliation",{"label":205,"value":621},"Infectious Laryngotracheitis, Newcastle Disease",[],[624,625],{"label":210,"value":211},{"label":213,"value":626},"Not applicable",[],{"keywords":629,"canonical":630,"hreflangs":631,"schemas":641,"title":448,"description":448},[169,218,219,173],"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Fammonia-toxicity\u002F",[632,633,635,637,639],{"lang":173,"href":630},{"lang":224,"href":634},"https:\u002F\u002Fkodibook.com\u002Fhi\u002Fdiseases\u002Fammonia-toxicity\u002F",{"lang":227,"href":636},"https:\u002F\u002Fkodibook.com\u002Fte\u002Fdiseases\u002Fammonia-toxicity\u002F",{"lang":230,"href":638},"https:\u002F\u002Fkodibook.com\u002Fta\u002Fdiseases\u002Fammonia-toxicity\u002F",{"lang":233,"href":640},"https:\u002F\u002Fkodibook.com\u002Fkn\u002Fdiseases\u002Fammonia-toxicity\u002F",[642],"{\"@context\":\"https:\u002F\u002Fschema.org\",\"@type\":\"TechArticle\",\"headline\":\"Ammonia Toxicity\",\"description\":\"Ammonia Toxicity\",\"identifier\":\"puid_poultry_01a051e7-a00c-7b45-b96b-398f2ced898e\",\"inLanguage\":\"en\",\"url\":\"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Fammonia-toxicity\u002F\",\"author\":{\"@type\":\"Organization\",\"name\":\"KodiBook\",\"url\":\"https:\u002F\u002Fkodibook.com\"}}","en\u002Fdiseases\u002Fammonia-toxicity","BvA4TGx6yyIOzgfBhCtxpZ3hZC-acilCMzN3q3RDB5A",{"id":646,"title":647,"author":13,"body":648,"category":169,"day":170,"description":647,"editorialReview":171,"extension":172,"featuredCategories":170,"futureReady":170,"handoff":170,"hero":170,"homepageSections":170,"language":173,"lastUpdated":174,"meta":786,"navigation":177,"path":788,"phase":170,"practical":789,"seo":821,"sequence":170,"stats":170,"stem":836,"tags":170,"translationVersion":238,"version":238,"whyKodiBook":170,"__hash__":837},"content\u002Fen\u002Fdiseases\u002Fascites.md","Ascites in Poultry",{"type":15,"value":649,"toc":778},[650,652,655,657,660,662,664,667,669,697,699,710,712,723,725,734,736,745,747,764,766],[18,651,21],{"id":20},[23,653,654],{},"A high-priority, non-infectious metabolic disorder of fast-growing broilers. Systemic hypoxia triggers polycythemia and pulmonary hypertension, leading to right ventricular dilation, right-sided heart failure, and massive fluid accumulation in the abdomen.",[18,656,29],{"id":28},[23,658,659],{},"Ascites (Pulmonary Hypertension Syndrome) results from a physiological mismatch between a broiler's rapid growth rate and its limited cardiopulmonary capacity. Environmental triggers (cold stress, poor ventilation, high altitude) induce systemic hypoxia, leading to increased blood viscosity and pulmonary arterial resistance. The chronic pressure overload destroys the right ventricle, causing transudation of fluid into the peritoneal cavity. Because it is metabolic, medicines do not cure it. Management relies entirely on moderating early growth rates (feed restriction, light schedules) and controlling environmental temperatures.",[18,661,36],{"id":35},[38,663,41],{"id":40},[23,665,666],{},"Metabolic > Non-Infectious",[38,668,48],{"id":47},[50,670,671,674,676,679,682,685,688,691,694],{},[53,672,673],{},"Prevalence in India: Common in fast-growing broilers",[53,675,477],{},[53,677,678],{},"Affected Species: Fast-growing broilers",[53,680,681],{},"Affected Age: Late-stage broilers (mortality greatest > 5 weeks)",[53,683,684],{},"Transmission: Non-infectious",[53,686,687],{},"Seasonality: Associated with cold weather\u002Fcold stress",[53,689,690],{},"Mortality: Approaching 100% in clinically affected birds showing abdominal distension",[53,692,693],{},"Morbidity: Incidence can exceed 5% in fast-growing flocks",[53,695,696],{},"Economic Importance: High (late-stage mortality, processing plant condemnation)",[38,698,77],{"id":76},[50,700,701,704,707],{},[53,702,703],{},"Early\u002FIntermediate: Reduced exercise tolerance, cyanotic combs and wattles, dyspnea",[53,705,706],{},"Advanced: Severe abdominal distension, reluctant waddling gait; targets Cardiovascular and Respiratory systems",[53,708,709],{},"Postmortem Findings: Large volume (up to 300mL) of clear, amber fluid with yellow fibrin clots in peritoneal cavity. Right ventricular dilatation and hypertrophy. Liver firm\u002Fwhite capsule.",[38,711,92],{"id":91},[50,713,714,717,720],{},[53,715,716],{},"Field Diagnosis: Fluid accumulation in abdomen, cyanosis",[53,718,719],{},"Laboratory Tests: Calculation of Right Ventricle-to-Total Ventricle (RV\u002FTV) ratio > 0.25",[53,721,722],{},"Differential Diagnosis: Colibacillosis (peritonitis), Hepatotoxicoses",[38,724,107],{"id":106},[50,726,727,730,732],{},[53,728,729],{},"Immediate Actions: Increase ventilation, reduce cold stress",[53,731,154],{},[53,733,335],{},[38,735,116],{"id":115},[50,737,738,740,742],{},[53,739,541],{},[53,741,544],{},[53,743,744],{},"Farm Management: Moderating growth rates via feed restriction\u002Flight-dark schedules (first 2 weeks); keeping dust\u002Fammonia low; controlling temperatures to prevent cold stress; SpO2 monitoring in breeding.",[18,746,131],{"id":130},[50,748,749,752,755,758,761],{},[53,750,751],{},"Morbidity Rate: > 5%",[53,753,754],{},"Mortality Rate: ~100% (of clinically affected)",[53,756,757],{},"Target Age: > 5 weeks",[53,759,760],{},"Diagnostic RV\u002FTV Ratio: > 0.25",[53,762,763],{},"Fluid Volume: Up to 300 mL",[18,765,146],{"id":145},[50,767,768,770,772,775],{},[53,769,573],{},[53,771,154],{},[53,773,774],{},"Breed Susceptibility: Fast-growing broilers",[53,776,777],{},"Predisposing Relationships: Co-infection with Aspergillus fumigatus or IBV damages lung parenchyma, triggering Ascites",{"title":159,"searchDepth":160,"depth":160,"links":779},[780,781,782,783,784,785],{"id":40,"depth":163,"text":41},{"id":47,"depth":163,"text":48},{"id":76,"depth":163,"text":77},{"id":91,"depth":163,"text":92},{"id":106,"depth":163,"text":107},{"id":115,"depth":163,"text":116},{"puid":787,"readingTime":163},"puid_poultry_01a051e7-a00c-7d5d-83fa-6055f96cf1c9","\u002Fen\u002Fdiseases\u002Fascites",{"entityId":159,"entityType":180,"language":173,"slug":790,"atAGlance":791,"whatYouMayNotice":797,"whyItMatters":804,"whatToCheck":809,"practicalProtocol":816,"preventionControl":817,"veterinaryEscalation":820,"hasPracticalData":177},"ascites",[792,793,795],{"label":184,"value":185},{"label":397,"value":794},"Late-stage broilers (mortality greatest > 5 weeks)",{"label":400,"value":796},"Non-infectious",[798,800,802],{"label":188,"value":799},"Reduced exercise tolerance, cyanotic combs and wattles, dyspnea",{"label":191,"value":801},"Severe abdominal distension, reluctant waddling gait; targets Cardiovascular and Respiratory systems",{"label":194,"value":803},"Large volume (up to 300mL) of clear, amber fluid with yellow fibrin clots in peritoneal cavity. Right ventricular dilatation and hypertrophy. Liver firm\u002Fwhite capsule.",[805,807],{"label":411,"value":806},"Approaching 100% in clinically affected birds showing abdominal distension",{"label":414,"value":808},"High (late-stage mortality, processing plant condemnation)",[810,812,814],{"label":199,"value":811},"Fluid accumulation in abdomen, cyanosis",{"label":202,"value":813},"Calculation of Right Ventricle-to-Total Ventricle (RV\u002FTV) ratio > 0.25",{"label":205,"value":815},"Colibacillosis (peritonitis), Hepatotoxicoses",[],[818,819],{"label":210,"value":211},{"label":213,"value":626},[],{"keywords":822,"canonical":823,"hreflangs":824,"schemas":834,"title":647,"description":647},[169,218,219,173],"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Fascites\u002F",[825,826,828,830,832],{"lang":173,"href":823},{"lang":224,"href":827},"https:\u002F\u002Fkodibook.com\u002Fhi\u002Fdiseases\u002Fascites\u002F",{"lang":227,"href":829},"https:\u002F\u002Fkodibook.com\u002Fte\u002Fdiseases\u002Fascites\u002F",{"lang":230,"href":831},"https:\u002F\u002Fkodibook.com\u002Fta\u002Fdiseases\u002Fascites\u002F",{"lang":233,"href":833},"https:\u002F\u002Fkodibook.com\u002Fkn\u002Fdiseases\u002Fascites\u002F",[835],"{\"@context\":\"https:\u002F\u002Fschema.org\",\"@type\":\"TechArticle\",\"headline\":\"Ascites in Poultry\",\"description\":\"Ascites in Poultry\",\"identifier\":\"puid_poultry_01a051e7-a00c-7d5d-83fa-6055f96cf1c9\",\"inLanguage\":\"en\",\"url\":\"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Fascites\u002F\",\"author\":{\"@type\":\"Organization\",\"name\":\"KodiBook\",\"url\":\"https:\u002F\u002Fkodibook.com\"}}","en\u002Fdiseases\u002Fascites","efud_6kNjUTBmrrRkc3HJ_mhtQeVzvc7_e-IpXYsKwM",{"id":839,"title":840,"author":13,"body":841,"category":169,"day":170,"description":840,"editorialReview":171,"extension":172,"featuredCategories":170,"futureReady":170,"handoff":170,"hero":170,"homepageSections":170,"language":173,"lastUpdated":174,"meta":1026,"navigation":177,"path":1028,"phase":170,"practical":1029,"seo":1054,"sequence":170,"stats":170,"stem":1069,"tags":170,"translationVersion":238,"version":238,"whyKodiBook":170,"__hash__":1070},"content\u002Fen\u002Fdiseases\u002Faspergillosis.md","Aspergillosis in Poultry",{"type":15,"value":842,"toc":1018},[843,847,870,872,875,877,880,882,884,887,889,911,913,924,926,937,939,947,949,960,962,972,974,986,990,998,1002,1006,1011,1015],[18,844,846],{"id":845},"entity-metadata","Entity Metadata",[50,848,849,852,855,858,861,864,867],{},[53,850,851],{},"Entity Name: Aspergillosis",[53,853,854],{},"Alternative Names: Brooder Pneumonia",[53,856,857],{},"Scientific Name: Aspergillus fumigatus \u002F Aspergillus flavus",[53,859,860],{},"Category: Fungal",[53,862,863],{},"Subcategory: Infectious Pathogen",[53,865,866],{},"Commercial Importance: Medium to High",[53,868,869],{},"India Relevance: Lung nodules in chicks",[18,871,21],{"id":20},[23,873,874],{},"An infectious, non-contagious fungal disease affecting poultry chicks. Inhaled hydrophobic conidia germinate deep within the lungs, releasing gliotoxins that induce severe granulomatous pneumonia and respiratory failure.",[18,876,29],{"id":28},[23,878,879],{},"Aspergillosis, or Brooder Pneumonia, is a severe fungal pathogen primarily affecting young chicks in hatchery and brooder systems. Small airborne conidia bypass upper respiratory filters, germinating into tissue-invading hyphae within the lungs and air sacs. They form characteristic yellow-white granulomas. There is no horizontal bird-to-bird transmission and no effective treatment in commercial poultry. Prevention is paramount, demanding strict disinfection of incubators and hatcheries, adequate ventilation, and absolute avoidance of damp or moldy litter. The lung damage from Aspergillosis is a direct predisposing trigger for Ascites (right-sided heart failure) in fast-growing broilers.",[18,881,36],{"id":35},[38,883,41],{"id":40},[23,885,886],{},"Fungal > Infectious Pathogen",[38,888,48],{"id":47},[50,890,891,894,896,899,902,905,908],{},[53,892,893],{},"Severity: Medium to High (high mortality in chicks)",[53,895,58],{},[53,897,898],{},"Affected Age: Young chicks \u003C 3 weeks of age; adults can develop chronic form",[53,900,901],{},"Transmission: Inhalation of airborne conidia (no direct bird-to-bird transmission)",[53,903,904],{},"Mortality: 5% to 50%",[53,906,907],{},"Morbidity: 1% to 10%",[53,909,910],{},"Economic Importance: Medium",[38,912,77],{"id":76},[50,914,915,918,921],{},[53,916,917],{},"Early\u002FIntermediate: Rapid, deep gasping (dyspnea) without tracheal rales, severe depression, lethargy, anorexia",[53,919,920],{},"Advanced: Nervous signs (torticollis, loss of equilibrium), ocular lesions (unilateral blindness); targets Respiratory system, CNS, and Eyes.",[53,922,923],{},"Postmortem Findings: Multiple discrete, yellow-white, firm cheesy granulomas (1-5mm) in lungs. Thickened, cloudy air sacs lined with dense bluish-green velvety mold.",[38,925,92],{"id":91},[50,927,928,931,934],{},[53,929,930],{},"Field Diagnosis: Gasping chicks without rales, lung nodules",[53,932,933],{},"Laboratory Tests: 10% KOH wet mounts of lung lesions (showing branching septate hyphae), Isolation on Sabouraud dextrose agar (smoky blue-green colonies)",[53,935,936],{},"Differential Diagnosis: Newcastle Disease, Infectious Bronchitis, Colibacillosis",[38,938,107],{"id":106},[50,940,941,944],{},[53,942,943],{},"Immediate Actions: Remove moldy litter, improve ventilation",[53,945,946],{},"Medicines: No effective treatment in commercial poultry",[38,948,116],{"id":115},[50,950,951,954,957],{},[53,952,953],{},"Vaccination: None exist",[53,955,956],{},"Biosecurity: Mitigated by standard Biosecurity Protocols, hatchery\u002Fincubator disinfection",[53,958,959],{},"Farm Management: Avoid damp\u002Fmoldy litter, maintain optimal ventilation",[18,961,131],{"id":130},[50,963,964,967,970],{},[53,965,966],{},"Morbidity Rate: 1% to 10%",[53,968,969],{},"Mortality Rate: 5% to 50%",[53,971,142],{},[18,973,146],{"id":145},[50,975,976,978,980,983],{},[53,977,573],{},[53,979,154],{},[53,981,982],{},"Biosecurity: Hatchery Sanitation, Litter moisture control",[53,984,985],{},"Predisposing Relationships: Triggers Ascites Syndrome (Pulmonary Hypertension)",[18,987,989],{"id":988},"evidence","Evidence",[50,991,992,995],{},[53,993,994],{},"Source: Poultry Disease Canonical Research; Comprehensive Guide to Avian Pathogens",[53,996,997],{},"Evidence Strength: Complete",[18,999,1001],{"id":1000},"references","References",[18,1003,1005],{"id":1004},"missing-information","Missing Information",[50,1007,1008],{},[53,1009,1010],{},"Prevalence in India and specific seasonality",[18,1012,1014],{"id":1013},"schema-coverage","Schema Coverage",[23,1016,1017],{},"Identity: Complete\nStructured Facts: Complete\nQuantitative Data: Complete\nRelationships: Complete\nReferences: Partial\nEvidence: Complete\nOverall Completeness: 95%",{"title":159,"searchDepth":160,"depth":160,"links":1019},[1020,1021,1022,1023,1024,1025],{"id":40,"depth":163,"text":41},{"id":47,"depth":163,"text":48},{"id":76,"depth":163,"text":77},{"id":91,"depth":163,"text":92},{"id":106,"depth":163,"text":107},{"id":115,"depth":163,"text":116},{"puid":1027,"readingTime":160},"puid_poultry_01a051e7-a00c-749d-ba18-a0c9a7a35bce","\u002Fen\u002Fdiseases\u002Faspergillosis",{"entityId":159,"entityType":180,"language":173,"slug":1030,"atAGlance":1031,"whatYouMayNotice":1033,"whyItMatters":1040,"whatToCheck":1041,"practicalProtocol":1048,"preventionControl":1049,"veterinaryEscalation":1053,"hasPracticalData":177},"aspergillosis",[1032],{"label":184,"value":185},[1034,1036,1038],{"label":188,"value":1035},"Rapid, deep gasping (dyspnea) without tracheal rales, severe depression, lethargy, anorexia",{"label":191,"value":1037},"Nervous signs (torticollis, loss of equilibrium), ocular lesions (unilateral blindness); targets Respiratory system, CNS, and Eyes.",{"label":194,"value":1039},"Multiple discrete, yellow-white, firm cheesy granulomas (1-5mm) in lungs. Thickened, cloudy air sacs lined with dense bluish-green velvety mold.",[],[1042,1044,1046],{"label":199,"value":1043},"Gasping chicks without rales, lung nodules",{"label":202,"value":1045},"10% KOH wet mounts of lung lesions (showing branching septate hyphae), Isolation on Sabouraud dextrose agar (smoky blue-green colonies)",{"label":205,"value":1047},"Newcastle Disease, Infectious Bronchitis, Colibacillosis",[],[1050,1051],{"label":210,"value":211},{"label":213,"value":1052},"Hatchery Sanitation, Litter moisture control",[],{"keywords":1055,"canonical":1056,"hreflangs":1057,"schemas":1067,"title":840,"description":840},[169,218,219,173],"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Faspergillosis\u002F",[1058,1059,1061,1063,1065],{"lang":173,"href":1056},{"lang":224,"href":1060},"https:\u002F\u002Fkodibook.com\u002Fhi\u002Fdiseases\u002Faspergillosis\u002F",{"lang":227,"href":1062},"https:\u002F\u002Fkodibook.com\u002Fte\u002Fdiseases\u002Faspergillosis\u002F",{"lang":230,"href":1064},"https:\u002F\u002Fkodibook.com\u002Fta\u002Fdiseases\u002Faspergillosis\u002F",{"lang":233,"href":1066},"https:\u002F\u002Fkodibook.com\u002Fkn\u002Fdiseases\u002Faspergillosis\u002F",[1068],"{\"@context\":\"https:\u002F\u002Fschema.org\",\"@type\":\"TechArticle\",\"headline\":\"Aspergillosis in Poultry\",\"description\":\"Aspergillosis in Poultry\",\"identifier\":\"puid_poultry_01a051e7-a00c-749d-ba18-a0c9a7a35bce\",\"inLanguage\":\"en\",\"url\":\"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Faspergillosis\u002F\",\"author\":{\"@type\":\"Organization\",\"name\":\"KodiBook\",\"url\":\"https:\u002F\u002Fkodibook.com\"}}","en\u002Fdiseases\u002Faspergillosis","vEe3XyPOFOWW2n0xsjgznHNoyWrGN4biTcj7LdHawAU",{"id":1072,"title":1073,"author":13,"body":1074,"category":169,"day":170,"description":1073,"editorialReview":171,"extension":172,"featuredCategories":170,"futureReady":170,"handoff":170,"hero":170,"homepageSections":170,"language":173,"lastUpdated":174,"meta":1267,"navigation":177,"path":1269,"phase":170,"practical":1270,"seo":1295,"sequence":170,"stats":170,"stem":1310,"tags":170,"translationVersion":238,"version":238,"whyKodiBook":170,"__hash__":1311},"content\u002Fen\u002Fdiseases\u002Favian-influenza.md","Avian Influenza in Poultry",{"type":15,"value":1075,"toc":1259},[1076,1078,1100,1102,1105,1107,1110,1112,1114,1116,1118,1144,1146,1157,1159,1170,1172,1185,1187,1198,1200,1214,1216,1228,1230,1240,1242,1247,1249,1254,1256],[18,1077,846],{"id":845},[50,1079,1080,1083,1086,1089,1092,1094,1097],{},[53,1081,1082],{},"Entity Name: Avian Influenza",[53,1084,1085],{},"Alternative Names: H5N1 \u002F H9N2, HPAI \u002F LPAI",[53,1087,1088],{},"Scientific Name: Influenza A viruses",[53,1090,1091],{},"Category: Viral",[53,1093,863],{},[53,1095,1096],{},"Commercial Importance: Critical",[53,1098,1099],{},"India Relevance: H5N1 requires mandatory culling under DAHD guidelines",[18,1101,21],{"id":20},[23,1103,1104],{},"A critical, highly contagious viral infectious disease affecting poultry. Highly Pathogenic Avian Influenza (HPAI, e.g., H5N1) causes pantropic systemic infection, vascular endothelial damage, and multi-organ failure, requiring culling. Low Pathogenic strains (LPAI, e.g., H9N2) restrict to respiratory\u002FGI tracts and cause drops in lay.",[18,1106,29],{"id":28},[23,1108,1109],{},"Avian Influenza is a critical viral pathogen transmitted globally via wild bird vectors. HPAI virulence is determined by multiple basic amino acids at the HA0 cleavage site, allowing ubiquitous intracellular proteases to trigger rapid, systemic multi-organ failure. The economic impact is critical; H5N1 mandates immediate flock culling and disrupts international trade. H9N2 (LPAI) leads to a drop in egg production. Prevention relies on absolute physical biosecurity, specifically wild bird netting (max 0.5 inch mesh wire) and concrete-elevated floors to exclude wild carriers.",[18,1111,36],{"id":35},[38,1113,41],{"id":40},[23,1115,44],{},[38,1117,48],{"id":47},[50,1119,1120,1123,1126,1129,1132,1135,1138,1141],{},[53,1121,1122],{},"Prevalence in India: Susceptible to outbreaks; managed under strict DAHD eradication guidelines",[53,1124,1125],{},"Severity: Critical (HPAI requires culling)",[53,1127,1128],{},"Affected Species: Poultry and wild avian species",[53,1130,1131],{},"Affected Age: All age groups",[53,1133,1134],{},"Transmission: Direct contact with respiratory secretions\u002Ffeces; indirect via wild bird vectors, contaminated equipment\u002Fwater",[53,1136,1137],{},"Mortality: Up to 100% within 48 hours for HPAI",[53,1139,1140],{},"Morbidity: Up to 100%",[53,1142,1143],{},"Economic Importance: Critical (trade bans, compulsory eradication)",[38,1145,77],{"id":76},[50,1147,1148,1151,1154],{},[53,1149,1150],{},"Early\u002FIntermediate: Severe depression, H9N2 causes drop in lay",[53,1152,1153],{},"Advanced: Sudden death, recumbency, cyanosis and swelling of comb\u002Fwattles, subcutaneous edema of head\u002Fshanks, petechial hemorrhages on unfeathered skin. Targets Vascular Endothelium, Systemic, Respiratory, Nervous, and GI systems.",[53,1155,1156],{},"Postmortem Findings: Diffuse hemorrhages throughout visceral organs (epicardium, myocardium, proventriculus), necrotizing pancreatitis, splenomegaly, severe pulmonary congestion and edema.",[38,1158,92],{"id":91},[50,1160,1161,1164,1167],{},[53,1162,1163],{},"Field Diagnosis: Sudden high mortality, cyanotic comb\u002Fwattles, subcutaneous edema",[53,1165,1166],{},"Laboratory Tests: RT-PCR targeting matrix (M) gene and subtype-specific primers (H5\u002FH7), virus isolation in SPF embryonated eggs (BSL-3). Sequencing of HA0 cleavage site.",[53,1168,1169],{},"Differential Diagnosis: Velogenic Newcastle Disease, Fowl Cholera, Infectious Laryngotracheitis",[38,1171,107],{"id":106},[50,1173,1174,1177,1180,1182],{},[53,1175,1176],{},"Immediate Actions: HPAI requires mandatory culling, movement bans, and restricted access (Control zones)",[53,1178,1179],{},"Supportive Care: Not applicable for HPAI",[53,1181,154],{},[53,1183,1184],{},"Veterinary Intervention: Strict DAHD regulatory enforcement and monthly\u002F21-day surveillance testing for compartmental freedom.",[38,1186,116],{"id":115},[50,1188,1189,1192,1195],{},[53,1190,1191],{},"Vaccination: None mentioned",[53,1193,1194],{},"Biosecurity: Wild Bird Netting (Max 0.5 inch mesh wire), concrete-elevated floors, separate entry with foot dips, quarterly medical check-ups for workers.",[53,1196,1197],{},"Farm Management: Compartmentalization and wildlife exclusion",[18,1199,131],{"id":130},[50,1201,1202,1205,1208,1211],{},[53,1203,1204],{},"Morbidity Rate: Up to 100%",[53,1206,1207],{},"Mortality Rate: Up to 100% within 48 hours (HPAI)",[53,1209,1210],{},"Netting Mesh Wire Size: Maximum 0.5 inch",[53,1212,1213],{},"Regulatory Threshold: IVPI > 1.2 or > 75% mortality requires sequencing",[18,1215,146],{"id":145},[50,1217,1218,1220,1222,1225],{},[53,1219,573],{},[53,1221,154],{},[53,1223,1224],{},"Biosecurity: Wild Bird Netting, DAHD Control Zones",[53,1226,1227],{},"Vector: Wild Birds",[18,1229,989],{"id":988},[50,1231,1232,1235,1238],{},[53,1233,1234],{},"Source: Comprehensive Guide to Avian Pathogens and Poultry Health Management; Poultry Disease Canonical Research",[53,1236,1237],{},"Organization: Department of Animal Husbandry and Dairying (DAHD), WOAH",[53,1239,997],{},[18,1241,1001],{"id":1000},[50,1243,1244],{},[53,1245,1246],{},"DAHD National Guidelines, WOAH standards",[18,1248,1005],{"id":1004},[50,1250,1251],{},[53,1252,1253],{},"Specific seasonality",[18,1255,1014],{"id":1013},[23,1257,1258],{},"Identity: Complete\nStructured Facts: Complete\nQuantitative Data: Complete\nRelationships: Complete\nEvidence: Complete\nReferences: Complete\nOverall Completeness: 98%",{"title":159,"searchDepth":160,"depth":160,"links":1260},[1261,1262,1263,1264,1265,1266],{"id":40,"depth":163,"text":41},{"id":47,"depth":163,"text":48},{"id":76,"depth":163,"text":77},{"id":91,"depth":163,"text":92},{"id":106,"depth":163,"text":107},{"id":115,"depth":163,"text":116},{"puid":1268,"readingTime":160},"puid_poultry_01a051e7-a00c-7ea1-9d9d-bdeec0f58c4b","\u002Fen\u002Fdiseases\u002Favian-influenza",{"entityId":159,"entityType":180,"language":173,"slug":1271,"atAGlance":1272,"whatYouMayNotice":1274,"whyItMatters":1281,"whatToCheck":1282,"practicalProtocol":1289,"preventionControl":1290,"veterinaryEscalation":1294,"hasPracticalData":177},"avian-influenza",[1273],{"label":184,"value":185},[1275,1277,1279],{"label":188,"value":1276},"Severe depression, H9N2 causes drop in lay",{"label":191,"value":1278},"Sudden death, recumbency, cyanosis and swelling of comb\u002Fwattles, subcutaneous edema of head\u002Fshanks, petechial hemorrhages on unfeathered skin. Targets Vascular Endothelium, Systemic, Respiratory, Nervous, and GI systems.",{"label":194,"value":1280},"Diffuse hemorrhages throughout visceral organs (epicardium, myocardium, proventriculus), necrotizing pancreatitis, splenomegaly, severe pulmonary congestion and edema.",[],[1283,1285,1287],{"label":199,"value":1284},"Sudden high mortality, cyanotic comb\u002Fwattles, subcutaneous edema",{"label":202,"value":1286},"RT-PCR targeting matrix (M) gene and subtype-specific primers (H5\u002FH7), virus isolation in SPF embryonated eggs (BSL-3). Sequencing of HA0 cleavage site.",{"label":205,"value":1288},"Velogenic Newcastle Disease, Fowl Cholera, Infectious Laryngotracheitis",[],[1291,1292],{"label":210,"value":211},{"label":213,"value":1293},"Wild Bird Netting, DAHD Control Zones",[],{"keywords":1296,"canonical":1297,"hreflangs":1298,"schemas":1308,"title":1073,"description":1073},[169,218,219,173],"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Favian-influenza\u002F",[1299,1300,1302,1304,1306],{"lang":173,"href":1297},{"lang":224,"href":1301},"https:\u002F\u002Fkodibook.com\u002Fhi\u002Fdiseases\u002Favian-influenza\u002F",{"lang":227,"href":1303},"https:\u002F\u002Fkodibook.com\u002Fte\u002Fdiseases\u002Favian-influenza\u002F",{"lang":230,"href":1305},"https:\u002F\u002Fkodibook.com\u002Fta\u002Fdiseases\u002Favian-influenza\u002F",{"lang":233,"href":1307},"https:\u002F\u002Fkodibook.com\u002Fkn\u002Fdiseases\u002Favian-influenza\u002F",[1309],"{\"@context\":\"https:\u002F\u002Fschema.org\",\"@type\":\"TechArticle\",\"headline\":\"Avian Influenza in Poultry\",\"description\":\"Avian Influenza in Poultry\",\"identifier\":\"puid_poultry_01a051e7-a00c-7ea1-9d9d-bdeec0f58c4b\",\"inLanguage\":\"en\",\"url\":\"https:\u002F\u002Fkodibook.com\u002Fen\u002Fdiseases\u002Favian-influenza\u002F\",\"author\":{\"@type\":\"Organization\",\"name\":\"KodiBook\",\"url\":\"https:\u002F\u002Fkodibook.com\"}}","en\u002Fdiseases\u002Favian-influenza","PUmqO6XWQZir_qsZVUBs3JClqL5_y_GCHImw15ZF9OQ",1789568965277]